Research Article

The Study of Naphthoquinones and Their Complexes with DNA by Using Raman Spectroscopy and Surface Enhanced Raman Spectroscopy: New Insight into Interactions of DNA with Plant Secondary Metabolites

Table 1

The increase (decrease) of the bands in the Raman spectrum of DNA after the modification by the studied naphthoquinones. The changes are expressed in the percentages (*the observation of Raman intensity of calf thymus DNA represents 100%; the change is counted separately for each band).

DNA-naphthoquinoneDNA*1,4-NaphthoquinoneBinaphthoquinoneJugloneLawsonePlumbagin

670 cm−1 vibrations of thymine10018119119018695
683 cm−1 vibrations of guanine100112101118101120
834 cm−1 B-conformation, phosphodiester bond1009698989899
1237 cm−1 vibrations of cytosine and thymine10085147129144102
1256 cm−1 vibrations of cytosine and thymine1008111695113100
1338 cm−1 vibrations of adenine and guanine10010211597114105
1376 cm−1 vibrations of thymine1007810910110786
1511 cm−1 vibrations of adenine100108118119116116
1578 cm−1 vibrations of adenine and guanine100125126123125123