Review Article

Optimal Management of the Critically Ill: Anaesthesia, Monitoring, Data Capture, and Point-of-Care Technological Practices in Ovine Models of Critical Care

Table 1

Validated ovine models of the Critical Care Research Group (CCRG) in Australia.

ModelTotal number of sheep required Publications

Extracorporeal membrane oxygenation (ECMO)72 [2, 1316]
Transfusion-related acute lung injury (TRALI)112[1720]
Cardiac mechanical assist device project (CMADP)9 + (ongoing study)[2124]
Colloids, red cells, aged red cells, sepsis, and haemorrhage (CRASH-S and CRASH-H)16 + (ongoing study)[20]
Smoke induced acute lung injury (S-ALI)20[25]
Brain stem death (BSD)24[26, 27]
Intracardiac echocardiography guided transseptal catheterization (ICETSC)20 + (ongoing study)[28]