Combined Analysis with Copy Number Variation Identifies Risk Loci in Lung Cancer
Table 2
Predicted CNVs in EAGLE.
Dataset
Chr.
Band
Start_pos.
End_pos.
Size (kb)
Type
Literature
EAGLE
1
1p36.22
12120766
12129342
8.6
Deletion
19513508; 16142337; 20676096
EAGLE
5
5q35.2
175888783
175901659
12.9
Deletion
—
EAGLE
8
8q23.3
113681735
113741162
59.4
Amplification
19324446
EAGLE
8
8q24.3
144694717
144728743
34.0
Deletion
18990762; 22142333
EAGLE
8
8q24.3
145079175
145118650
39.5
Deletion
18990762; 22142333
EAGLE
9
9q32
114406899
114414974
8.1
Deletion
18798555; 15580306; 7512370
EAGLE
9
9q34.3
138620438
138641922
21.5
Deletion
16740712
EAGLE
10
10q22.3
80766077
80778488
12.4
Deletion
18758299; 20651054
EAGLE
11
11q13.1
65012165
65051406
39.2
Deletion
11274644
EAGLE
13
13q21.1
56772821
56803216
30.4
Amplification
20200074; 19324446
EAGLE
16
16p13.3
1951065
1994156
43.1
Deletion
17086460
EAGLE
17
17q21.1
35509120
35510616
1.5
Deletion
16733218; 11378338
EAGLE
17
17q25.3
73635123
73655682
20.6
Deletion
17086460
EAGLE
17
17q25.3
77848326
78009203
160.9
Deletion
17086460
EAGLE
18
18p11.32
2580764
2629683
48.9
Deletion
19190329
EAGLE
18
18q22.1
64897188
64906488
9.3
Amplification
—
EAGLE
19
19p13.3
1046061
1126396
80.3
Deletion
21521776
EAGLE
19
19p13.3
1994271
2001823
7.6
Deletion
21521776
EAGLE
19
19p13.3
2050820
2079054
28.2
Deletion
21521776
EAGLE
20
20q13.33
61642713
61668792
26.1
Abnormal
17304513
EAGLE
21
21q22.3
45769452
45788806
19.4
Deletion
15900585
EAGLE
22
22q13.1
37667446
37704618
37.2
Deletion
10515681; 15262437
This table reports the 22 predicted CNVs summarized from risk loci (Table S2) in EAGLE. The Literature shows the PubMed unique identifier (PMID) for previous papers that provide the risk evidence for these loci. See Section 4 for detailed information.
