Coronal view of a fused 18F-FDG PET/CT image of a culture proven infected vascular prosthetic graft. In this particular case, a 70-year-old male patient underwent an ileofemoral bypass from the left to right side using Dacron. After 10 years the patient was readmitted with an occlusion of the bypass possibly due to a suture aneurysm. CT scan revealed an occlusion of the bypass with no signs of infection. 18F-FDG PET/CT scanning clearly showed increased FDG uptake at the level of the suture aneurysm. Ultimately, Escherichia coli were cultured from the graft.