Table 7: Brain areas with reduced GM volume in ALS patients with left limb-onset and corresponding normal controls ( , uncorrected).

Brain anatomical regions BA
region
MNI coordinates of
peak voxels (mm)
Cluster
size
value value

R_precentral gyri4, 610−1848894.070.0008
R_superior frontal gyri614−2622093.700.0008
R_supplementary motor areas612−658283.420.0002
R_postcentral gyri336−2842334.090.0008
R_supramarginal gyri4062−4022262.120.0002
L_precentral gyri4, 6−34−14541113.560.0004
L_parietal opercular−52−3820283.920.0002
L_supramarginal gyri40−54−4618933.420.0002
L_angular gyri39−44−5212483.360.0004

L: left; R: right.