Research Article

Peripheral Injection of SB203580 Inhibits the Inflammatory-Dependent Synthesis of Proinflammatory Cytokines in the Hypothalamus

Figure 3

Effect of lipopolysaccharide (LPS) (400 ng/kg; i.v./7 days) and SB203580 (500 μg/kg) injections on the gene expression of IL-6 (a) and IL-6R (b) in the hypothalamus on day 7 of the experiment. a, b, c— (indicate values that differ significantly from the control, SB203580 control, and LPS treated groups, resp., according to the Mann-Whitney test). Data are presented as a mean value ± S.E.M.
475152.fig.003a
(a)
475152.fig.003b
(b)