Extracts from Vatica diospyroides Type SS Fruit Show Low Dose Activity against MDA-MB-468 Breast Cancer Cell-Line via Apoptotic Action
Figure 1
(a–l) Dot plots from FACS analysis of MDA-MB-468 cells treated with acetone extract of pericarp (a–c), methanolic extract of pericarp (d–f), acetone extract of cotyledon (g–i), and methanolic extract of cotyledon (j–l). All these extracts from V. diospyroides type SS fruit were used at half IC50 dose level and compared across a range of treatment times (24–72 h).
(a) Cells treated with acetone extract of pericarp for 24 hours
(b) Cells treated with acetone extract of pericarp for 48 hours
(c) Cells treated with acetone extract of pericarp for 72 hours
(d) Cells treated with methanolic extract of pericarp for 24 hours
(e) Cells treated with methanolic extract of pericarp for 48 hours
(f) Cells treated with methanolic extract of pericarp for 72 hours
(g) Cells treated with acetone extract of cotyledon for 24 hours
(h) Cells treated with acetone extract of cotyledon for 48 hours
(i) Cells treated with acetone extract of cotyledon for 72 hours
(j) Cells treated with methanolic extract of cotyledon for 24 hours
(k) Cells treated with methanolic extract of cotyledon for 48 hours
(l) Cells treated with methanolic extract of cotyledon for 72 hours
