Research Article

Extracts from Vatica diospyroides Type SS Fruit Show Low Dose Activity against MDA-MB-468 Breast Cancer Cell-Line via Apoptotic Action

Table 1

Half-inhibitory dose concentrations (IC50) of both acetone and methanolic extracts from V. diospyroides type SS fruit against MDA-MB-468 cell-lines.

Fruit partSolventMDA-MB-468 cell
IC50, mean ± SD (μg/mL)Activity

CotyledonAcetone1.60 ± 0.00aVery strong
Methanol3.50 ± 0.60aVery strong
PericarpAcetone17.45 ± 2.10cModerate
Methanol10.64 ± 3.22bModerate

Statistically significant differences at were determined by one-way ANOVA using SPSS version 11.0 program. Different superscripts (a, b, or c) indicate significant differences according to Tukey’s multiple comparison test. Each result is based on three replicates.