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BioMed Research International
Volume 2014, Article ID 483136, 8 pages
http://dx.doi.org/10.1155/2014/483136
Research Article

Helicobacter pylori Is Not Eradicated after Triple Therapy: A Nested PCR Based Study

1Department of Microbiology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh 221005, India
2Department of Medicine, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh 221005, India
3Department of Gastroenterology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh 221005, India

Received 27 February 2014; Revised 7 June 2014; Accepted 7 June 2014; Published 23 June 2014

Academic Editor: Kathleen Montone

Copyright © 2014 Saurabh Kumar Patel et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. R. W. M. van der Hulst, J. J. Keller, E. A. J. Rauws, and G. N. J. Tytgat, “Treatment of Helicobacter pylori infection: a review of the world literature,” Helicobacter, vol. 1, no. 1, pp. 6–19, 1996. View at Publisher · View at Google Scholar · View at Scopus
  2. International Agency for Research on Cancer, Schistosomes, Liver Flukes and Helicobacter pylori, vol. 61 of IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, International Agency for Research on Cancer, Lyon, France, 1994.
  3. K. Kimura, K. Ido, K. Saifuku et al., “A 1-h topical therapy for the treatment of Helicobacter pylori infection,” American Journal of Gastroenterology, vol. 90, no. 1, pp. 60–63, 1995. View at Google Scholar · View at Scopus
  4. J. J. Y. Sung, S. C. S. Chung, T. K. W. Ling et al., “Antibacterial treatment of gastric ulcers associated with Helicobacter pylori,” The New England Journal of Medicine, vol. 332, pp. 139–142, 1995. View at Google Scholar
  5. E. Bayerdorffer, G. A. Mannes, A. Sommer et al., “Long-term follow-up after eradication of Helicobacter pylori with a combination of omeprazole and amoxycillin,” Scandinavian Journal of Gastroenterology, vol. 28, supplement 196, pp. 19–25, 1993. View at Publisher · View at Google Scholar · View at Scopus
  6. D. Y. Graham, A. R. Opekun, and P. D. Klein, “Clarithromycin for the eradication of Helicobacter pylori,” Journal of Clinical Gastroenterology, vol. 16, no. 4, pp. 292–294, 1993. View at Publisher · View at Google Scholar · View at Scopus
  7. R. P. H. Logan, P. A. Gummett, H. D. Schaufelberger et al., “Eradication of Helicobacter pylori with clarithromycin and omeprazole,” Gut, vol. 35, no. 3, pp. 323–326, 1994. View at Publisher · View at Google Scholar · View at Scopus
  8. H. Xia, M. A. Daw, S. Sant, S. Beattie, C. T. Keane, and C. A. O'Morain, “Clinical efficacy of triple therapy in Helicobacter pylori-associated duodenal ulcer,” European Journal of Gastroenterology & Hepatology, vol. 5, no. 3, pp. 141–144, 1993. View at Publisher · View at Google Scholar · View at Scopus
  9. T. U. Wheeldon, T. T. Hoang, D. C. Phung, A. Björkman, M. Granström, and M. Sörberg, “Long-term follow-up of Helicobacter pylori eradication therapy in Vietnam: reinfection and clinical outcome,” Alimentary Pharmacology & Therapeutics, vol. 21, no. 8, pp. 1047–1053, 2005. View at Publisher · View at Google Scholar
  10. T. Okimoto, K. Murakami, R. Sato et al., “Is the recurrence of Helicobacter pylori infection after eradication therapy resultant from recrudescence or reinfection, in Japan,” Helicobacter, vol. 8, no. 3, pp. 186–191, 2003. View at Publisher · View at Google Scholar · View at Scopus
  11. J. P. Gisbert, I. G. Arata, D. Boixeda et al., “Role of partner's infection in reinfection after Helicobacter pylori eradication,” European Journal of Gastroenterology and Hepatology, vol. 14, no. 8, pp. 865–871, 2002. View at Publisher · View at Google Scholar · View at Scopus
  12. P. Hildebrand, P. Bardhan, L. Rossi et al., “Recrudescence and reinfection with Helicobacter pylori after eradication therapy in Bangladeshi adults,” Gastroenterology, vol. 121, no. 4, pp. 792–798, 2001. View at Publisher · View at Google Scholar · View at Scopus
  13. H. X. Xia, H. J. Windle, D. G. Marshall, C. J. Smyth, C. T. Keane, and C. A. O'Morain, “Recrudescence of Helicobacter pylori after apparently successful eradication: novel application of randomly amplified polymorphic DNA fingerprinting,” Gut, vol. 37, no. 1, pp. 30–34, 1995. View at Publisher · View at Google Scholar · View at Scopus
  14. V. Singh, S. Mishra, G. R. K. Rao et al., “Evaluation of nested PCR in detection of Helicobacter pylori targeting a highly conserved gene: HSP60,” Helicobacter, vol. 13, no. 1, pp. 30–34, 2008. View at Publisher · View at Google Scholar · View at Scopus
  15. S. K. Patel, C. B. Pratap, A. K. Verma, A. K. Jain, V. K. Dixit, and G. Nath, “Pseudomonas fluorescens-like bacteria from the stomach: a microbiological and molecular study,” World Journal of Gastroenterology, vol. 19, no. 7, pp. 1056–1067, 2013. View at Publisher · View at Google Scholar · View at Scopus
  16. S.-A. Ho, J. A. Hoyle, F. A. Lewis et al., “Direct polymerase chain reaction test for detection of Helicobacter pylori in humans and animals,” Journal of Clinical Microbiology, vol. 29, no. 11, pp. 2543–2549, 1991. View at Google Scholar · View at Scopus
  17. B. E. Dunn, H. Cohen, and M. J. Blaser, “Helicobacter pylori,” Clinical Microbiology Reviews, vol. 10, no. 4, pp. 720–741, 1997. View at Google Scholar · View at Scopus
  18. S. P. Cole, D. Cirillo, M. F. Kagnoff, D. G. Guiney, and L. Eckmann, “Coccoid and spiral Helicobacter pylori differ in their abilities to adhere to gastric epithelial cells and induce interleukin-8 secretion,” Infection and Immunity, vol. 65, no. 2, pp. 843–846, 1997. View at Google Scholar · View at Scopus
  19. M. Hammar, T. Tyszkiewicz, T. Wadström, and P. W. O'Toole, “Rapid detection of Helicobacter pylori in gastric biopsy material by polymerase chain reaction,” Journal of Clinical Microbiology, vol. 30, no. 1, pp. 54–58, 1992. View at Google Scholar · View at Scopus
  20. N. S. Taylor, J. G. Fox, N. S. Akopyants et al., “Long-term colonization with single and multiple strains of Helicobacter pylori assessed by DNA fingerprinting,” Journal of Clinical Microbiology, vol. 33, no. 4, pp. 918–923, 1995. View at Google Scholar · View at Scopus
  21. S. M. Salama, Q. Jiang, N. Chang, R. W. Sherbaniuk, and D. E. Taylor, “Characterization of chromosomal DNA profiles from Helicobacter pylori strains isolated from sequential gastric biopsy specimens,” Journal of Clinical Microbiology, vol. 33, no. 9, pp. 1496–1497, 1995. View at Google Scholar · View at Scopus
  22. W. Tee, J. Lambert, R. Smallwood, M. Schembri, B. C. Ross, and B. Dwyer, “Ribotyping of Helicobacter pylori from clinical specimens,” Journal of Clinical Microbiology, vol. 30, no. 6, pp. 1562–1567, 1992. View at Google Scholar · View at Scopus
  23. M. Costas, R. J. Owen, J. Bickley, and D. R. Morgan, “Molecular techniques for studying the epidemiology of infection by Helicobacter pylori,” Scandinavian Journal of Gastroenterology, vol. 26, no. 181, pp. 20–32, 1991. View at Publisher · View at Google Scholar · View at Scopus
  24. R. J. Owen, J. Bickley, M. Costas, and D. R. Morgan, “Genomic variation in Helicobacter pylori: application to identification of strains,” Scandinavian Journal of Gastroenterology, vol. 26, no. 181, pp. 43–50, 1991. View at Google Scholar · View at Scopus
  25. J. H. Oudbier, W. Langenberg, E. A. J. Rauws, and C. Bruin-Mosch, “Genotypical variation of Campylobacter pylori from gastric mucosa,” Journal of Clinical Microbiology, vol. 28, no. 3, pp. 559–565, 1990. View at Google Scholar · View at Scopus
  26. W. Langenberg, E. A. J. Rauws, H. J. Houthoff et al., “Follow-up study of individuals with untreated Campylobacter pylori-associated gastritis and of noninfected persons with non-ulcer dyspepsia,” The Journal of Infectious Diseases, vol. 157, no. 6, pp. 1245–1249, 1988. View at Publisher · View at Google Scholar · View at Scopus
  27. K. Schutze, E. Hentschel, B. Dragosics, and A. M. Hirschl, “Helicobacter pylori reinfection with identical organisms: transmission by the patients' spouses,” Gut, vol. 36, no. 6, pp. 831–833, 1995. View at Publisher · View at Google Scholar · View at Scopus
  28. L. Cellini, N. Allocati, D. Angelucci et al., “Coccoid Helicobacter pylori not culturable in vitro reverts in mice,” Microbiology and Immunology, vol. 38, no. 11, pp. 843–850, 1994. View at Publisher · View at Google Scholar · View at Scopus
  29. S. E. Perkins, L. L. Yan, Z. Shen, A. Hayward, J. C. Murphy, and J. G. Fox, “Use of PCR and culture to detect Helicobacter pylori in naturally infected cats following triple antimicrobial therapy,” Antimicrobial Agents and Chemotherapy, vol. 40, no. 6, pp. 1486–1490, 1996. View at Google Scholar · View at Scopus
  30. A. Rollan, R. Giancaspero, F. Fuster et al., “The long-term reinfection rate and the course of duodenal ulcer disease after eradication of Helicobacter pylori in a developing country,” American Journal of Gastroenterology, vol. 95, no. 1, pp. 50–56, 2000. View at Publisher · View at Google Scholar · View at Scopus
  31. A. Makristathis, W. Barousch, E. Pasching et al., “Two enzyme immunoassays and PCR for detection of Helicobacter pylori in stool specimens from pediatric patients before and after eradication therapy,” Journal of Clinical Microbiology, vol. 38, no. 10, pp. 3710–3714, 2000. View at Google Scholar · View at Scopus