Thai Massage, and Thai Herbal Compress versus Oral Ibuprofen in Symptomatic Treatment of Osteoarthritis of the Knee: A Randomized Controlled Trial

Table 6

Mean changes from baseline in VAS assessing stiffness, Lequesne’s functional index, and time for climbing up ten steps in intent-to-treat patients ().

Variable	Treatment group	Week 0-1	Week 0–2	Week 0–3
VAS assessing stiffness (mm)
Morning stiffness	TM	−17.25 ± 17.99	−30.15 ± 21.86	−42.50 ± 21.97
	THC	−16.90 ± 21.84	−34.50 ± 28.86	−46.25 ± 29.68
	Ibuprofen	−20.90 ± 23.68	−30.75 ± 29.94	−38.40 ± 31.44
Stiffness after rest	TM	−16.95 ± 16.37	−30.20 ± 19.40	−33.85 ± 25.12
	THC	−19.10 ± 19.81	−31.95 ± 23.53	−39.15 ± 23.78
	Ibuprofen	−18.40 ± 23.25	−29.00 ± 30.25	−36.80 ± 29.47
Total stiffness^a	TM	−34.20 ± 29.54	−60.35 ± 38.37	−76.35 ± 41.56
	THC	−36.00 ± 36.45	−66.45 ± 48.24	−85.40 ± 49.46
	Ibuprofen	−39.30 ± 44.51	−59.75 ± 59.42	−75.20 ± 59.45
Lequesne’s functional index (score)	TM	−2.33 ± 2.30	−4.10 ± 3.01	−5.78 ± 2.41
	THC	−2.58 ± 2.82	−4.95 ± 3.45	−6.73 ± 3.45*
	Ibuprofen	−2.50 ± 2.33	−4.35 ± 2.47	−4.85 ± 2.84
Time for climbing up ten steps (second)	TM	−1.30 ± 2.52	−2.70 ± 3.15	−3.55 ± 3.33
	THC	−2.85 ± 4.64	−4.65 ± 4.08	−5.60 ± 4.57
	Ibuprofen	−1.60 ± 1.93	−3.15 ± 3.42	−3.90 ± 4.00

Data represent mean ± SD. ^aSummation of VAS that assessed morning stiffness and stiffness after rest.
*Statistical significance versus ibuprofen (P = 0.048).