Research Article

Expression Profiles of Epithelial-Mesenchymal Transition-Associated Proteins in Epithelial Ovarian Carcinoma

Table 2

Expression of Snail according to the clinicopathologic variables in serous adenocarcinomas ( ).

VariablesSnaillow, (%)Snailhigh, (%)P value

Stage
 I/II1 (5.3)18 (94.7)0.574
 III/IV4 (9.5)38 (90.5)
Grade
 10 (0)5 (100)0.591
 23 (12)22 (88)
 32 (6.5)29 (93.5)
LN metastasis
 No4 (9.3)39 (90.7)0.666
 Yes1 (5.9)16 (94.1)
Responses
 CR/PR5 (10.2)44 (89.8)0.561
 SD/PD0 (0)3 (100)
Platinum sensitivity*
 Sensitive4 (12.5)28 (87.5)0.594
 Intermediate1 (7.1)13 (92.9)
 Resistant0 (0)6 (100)

LN: lymph node; CR: complete response; PR: partial response; SD: stable disease; PD: progressive disease.
*Platinum sensitivity was defined according to the time interval from the date of last chemotherapy cycle to the first evidence of recurrence; sensitive when the interval was >12 months, intermediate when the interval was >6 months and <12 months, and resistant when the interval was <6 months.