Single Amino Acid Arginine Deprivation Triggers Prosurvival Autophagic Response in Ovarian Carcinoma SKOV3
Figure 7
Effect of the autophagy inhibitor chloroquine (CQ) on SKOV3 cells viability and proliferative potential. Histograms showing cell survival and ability to resume proliferation after arginine resupplementation in cells deprived of arginine (AFM) (a) or cotreated with CQ (b). After the indicated periods of the treatment, the medium was changed to CM and cells were allowed to grow for additional 72 h. Viable cell numbers were determined by the trypan blue exclusion test. 100% is the number of cells at zero time point. .
