FSim: A Novel Functional Similarity Search Algorithm and Tool for Discovering Functionally Related Gene Products

Figure 2

The cumulative distribution functions of the two groups of FSim-calculated functional similarity scores for the P53 pathway. The -axis is the FSim functional similarity scores and the -axis is the cumulative distribution functions. The distribution of the functional similarity scores of the P53 pathway genes (in red) is systematically higher than the distribution of the functional similarity scores of the other genes (in green), with the value of Kolmogorov-Smirnov test less than .