Role of Dried Fruits of Carissa carandas as Anti-Inflammatory Agents and the Analysis of Phytochemical Constituents by GC-MS
Table 3
Anti-inflammatory activity of methanol extract of dried fruit of Carissa carandas.
Group
Sample
Amount of sample
Increase in paw volume (min)
% decrease in paw volume
30
60
90
120
I
Control
1 mL/kg
0.198 ± 0.01
0.35 ± 0.027
0.64 ± 0.021
0.77 ± 0.005
—
II
Standard
50 mg/kg
0.13 ± 0.021**
0.17 ± 0.016**
0.35 ± 0.021**
0.27 ± 0.016**
80.63
III
Methanol extract
100 mg/kg
0.21 ± 0.005**
0.29 ± 0.005**
0.48 ± 0.005**
0.57 ± 0.005**
33.7
IV
Methanol extract
200 mg/kg
0.19 ± 0.01**
0.22 ± 0.01**
0.4 ± 0.01**
0.45 ± 0.01**
60.95
V
Methanol extract
400 mg/kg
0.17 ± 0.01**
0.2 ± 0.01**
0.34 ± 0.05**
0.37 ± 0.01**
76.12
The mean difference is significant at the 0.05 level, when compared to the control group.
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