BioMed Research International / 2014 / Article / Tab 1

Research Article

The Association between Autoantibodies and Peripheral Neuropathy in Lupus Nephritis

Table 1

Clinical and laboratory data of lupus nephritis with or without peripheral neuropathy.

SLE-LN with neuropathy
( )
SLE-LN without neuropathy
( )

Age 0.073
Classification of peripheral neuropath
 Autonomic neuropathy40ND
 Mixed sensory-motor polyneuropathy130ND
 Sensory polyneuropathy20ND
Autoantibody titers, median (IQR)
 Anti-β2 glycoprotein I5.7 (2.65–6.25)3.8 (2.4–5.6)0382
 Anti-cardiolipin IgG21.6 (7.68–26.7)6.5 (3.3–15.0)0.071
 Anti-cardiolipin IgM3.8 (0.75–49.3)2.2 (1.2–4.5)0.429
 Anti-Ro240 (106–240.0)92.3 (0.9–240.0)0.009*
 Anti-La1.9 (1–51.4)1.1 (0.4–6.3)0.095
 Anti-RNP26.7 (2.3–77.9)2.5 (1.4–27.9)0.078
 anti-Smith IgG1.4 (0.5–2.9)0.6 (0.3–2.7)0.15
 Anti-scl-700.35 (0.18–0.63)0.4 (0.2–0.6)0.699
 Anti-Jo10.5 (0.1–0.5)0.2 (0.1–0.5)0.459
 Anti-centromere IgG0.5 (0.2–1.0)0.5 (0.2–1.0)0.457
 p-ANCA0.9 (0.6–2.1)0.9 (0.5–1.4)0.804
 c-ANCA1.1 (0.48–1.43)0.9 (0.5–1.4)0.855

Four patients had both polyneuropathy and autonomic neuropathy.
SLE-LN: systemic lupus erythematosus with lupus nephritis; p-ANCA: peri-nuclear anti-neutrophil cytoplasmic antibody; c-ANCA: cytoplasmic anti-neutrophil cytoplasmic antibody; IQR: interquartile range; CI: confidence interval; ND: not done.

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