Research Article
Investigation of NF-κB1 and NF-κBIA Gene Polymorphism in Non-Small Cell Lung Cancer
Table 2
Distribution of NF-κB1 and NF-κBIA genotypes and allele in NSCLC patients and controls.
| | Genotypes/alleles | Controls (%) | Patients (%) | O.R (95% CI) | value |
| | NF-κB1 | | | | | | II | 46 (46.47) | 35 (36.84) | Reference | | | ID | 47 (47.47) | 44 (46.32) | 1.23 (0.67–2.25) | 0.500 | | DD | 6 (6.06) | 16 (16.84) | 3.50 (1.24–9.87) | 0.014 | | ID + DD | 53 (53.53) | 60 (63.16) | 1.49 (0.84–2.64) | 0.174 | | I allele | 139 (70.2) | 114 (60) | Reference | | | D allele | 59 (29.8) | 76 (40) | 1.57 (1.03–2.39) | 0.035 | | NF-κBIA | | | | | | AA | 21 (21.21) | 17 (17.9) | Reference | | | AG | 45 (45.46) | 45 (47.36) | 1.24 (0.58–2.65) | 0.587 | | GG | 33 (33.33) | 33 (34.74) | 1.24 (0.55–2.75) | 0.605 | | AG + GG | 78 (78.79) | 78 (82.1) | 1.24 (0.61–2.52) | 0.561 | | A allele | 87 (43.94) | 79 (41.58) | Reference | | | G allele | 111 (56.06) | 111 (58.42) | 1.10 (0.74–1.65) | 0.639 |
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O.R: Odds ratio; CI: confidence interval.
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