Animal Model of Acid-Reflux Esophagitis: Pathogenic Roles of Acid/Pepsin, Prostaglandins, and Amino Acids

Figure 10

Buffering capability of various amino acids against HCl in vitro. L-alanine (500 mg/kg), L-arginine (250 mg/kg), L-glutamine (750 mg/kg), or glycine (750 mg/kg) was suspended or dissolved in a 0.5% CMC solution, and 1 mL of these solutions was titrated by the addition of 150 mM HCl. Changes in the pH of the solution were determined by a pH meter (from [17] after modifications).