Pharmacological Treatments in Gambling Disorder: A Qualitative Review

Table 3

Mood stabilizers and atypical antipsychotics in gambling disorder.

Study	Drug tested and mean-range dosage	Study design	Study group and duration	Findings
Mood stabilizers and atypical antipsychotics in GD
Hollander et al. 2005 [17]	Lithium carbonate; mean dose 1170 mg/day	Double-blind; placebo-controlled	40 patients; with bipolar comorbid; for 10 weeks	Lithium is significantly superior to placebo
Berlin et al. 2013 [38]	Topiramate; 25–300 mg/day	Double-blind; placebo-controlled	42 patients; for 14 weeks	Topiramate is not significantly superior to placebo
McElroy et al. 2008 [19]	Olanzapine; 2.5–15 mg/day	Double-blind; placebo-controlled	42 patients; for 12 weeks	Olanzapine is not significantly superior to placebo
Fong et al. 2008 [18]	Olanzapine; 2.5–10 mg/day	Double-blind; placebo-controlled	23 patients; for 7 weeks	Olanzapine is not significantly superior to placebo