Therapeutic Efficacy of Vitamin E 𝜹-Tocotrienol in Collagen-Induced Rat Model of Arthritis

Table 1

Effect of delta-tocotrienol on percentage changes in paw edema in arthritis rats.

Days	Left hind limb joint			Right hind limb joint
	Arthritis	Arthritis + tocotrienol	Arthritis + glucosamine	Arthritis	Arthritis + tocotrienol	Arthritis + glucosamine
Day 25	100 ± 2.2	100 ± 1.2	100 ± 1.5	100 ± 1.3	100 ± 2.4	100 ± 2.5
Day 30	98.37 ± 3.4	94.74 ± 2.8*	92.35 ± 1.2	94.87 ± 4.1	92.05 ± 3.7	94.76 ± 3.2
Day 35	95.93 ± 3.7	88.05 ± 3.8*	90.91 ± 4.1*	92.71 ± 2.1	89.94 ± 2.8*	91.45 ± 2.4
Day 40	92.05 ± 4.8	84.35 ± 5.4*	88.75 ± 3.4*	90.19 ± 3.7	85.45 ± 2.9*	88.91 ± 1.1*
Day 45	88.42 ± 4.9	80.75 ± 4.3^*◆	87.41 ± 2.8	88.99 ± 3.9	82.41 ± 4.1^*◆	84.65 ± 2.4*
Day 50	87.24 ± 2.8	75.35 ± 2.7^*◆	82.15 ± 3.8*	87.31 ± 2.8	78.94 ± 2.1^*◆	79.43 ± 2.8*

Data are expressed as mean ± standard error of six rats per group. *𝑃<0.05: arthritis versus other groups; ^◆𝑃<0.05: arthritis with tocotrienol versus arthritis with glucosamine groups.