Booster Vaccination: The Role of Reduced Antigen Content Vaccines as a Preschool Booster

Table 3

Seroprotection rate (%) up to 10 years after booster vaccination of children.

Country and/or author	Age (years)	Vaccine	Timing	Seroprotection rate (%)
				Anti-D	Anti-T	Antipolio type 1	Antipolio type 2	Antipolio type 3	PT	FHA	PRN
Cheuvart et al., 2004 [34]	4–6	dTap	After 1 month; After 3.5 years	100; 100	—; —	—; —	—; —	—; —	—; —	—; —	—; —
		DTaP	After 1 month; After 3.5 years	100; 100	—; —	—; —	—; —	—; —	—; —	—; —	—; —
		Td	After 1 month; After 3.5 years	100; 100	—; —	—; —	—; —	—; —	—; —	—; —	—; —
Germany; Sänger et al., 2007 [23]	4–8	dTap – IPV	After 1 month; After 1 year	100; 100	99.9; 99.8	100; 100	100; 100	100; 99.8	99.6; 81.2	100; 100	99.9; 98.1
		dTap + IPV	After 1 month; After 1 year	100; 100	100; 98.8	100; 100	100; 100	100; 98.6	99.2; 75.3	100; 98.8	100; 97.5
Thailand; Kosuwon et al., 2003 [35]	4–6	dTap	After 1 month	99.4	100	—	—	—	96.9	96.9	95.1
Taiwan; Huang et al., 2005 [20]	6–8	dTap	After 1 month	100	100	—	—	—	94.9	98.3	96.6
Germany; Meyer et al., 2008 [27]	4–6	dTap	After 1 month; After 3.5 years	100; 100	100; 98.4	—; —	—; —	—; —	100; 58.7	100; 100	100; 99.2
		DTaP	After 1 month; After 3.5 years	100; 100	100; 98.5	—; —	—; —	—; —	100; 60.6	100; 100	100; 100
		dT	After 1 month; After 3.5 years	100; 100	100; 100	—; —	—; —	—; —	—; —	—; —	—; —
Finland; Mertsola et al., 2010 [40]	20–24	dTap	After 10 years	98.6	97.3	—	—	—	61.3	100	96.0