Cytogenetic as an Important Tool for Diagnosis and Prognosis for Patients with Hypocellular Primary Myelodysplastic Syndrome

Table 1

Cytogenetic analysis in 105 patients with hypocellular primary MDS.

Case	Age; (years)	FAB	Karyotype	IPSS	Evolution from MDS to AML/time to AML transformation; (months)
1	7	RA	46, XX[25]	Int-1	No
2	16	RA	46, XY[33]	Int-1	No
3	53	RA	46, XY[42]	Int-1	No
4	61	RA	46, XX[20]	Int-1	No
5	17	RA	46, XX[20]	Int-1	No
6	12	RA	46, XX[49]	Int-1	No
7	27	RA	46, XY, del(17)(p12)[5]/46, XY[23]	Int-1	No
8	26	RA	46, XX[30]	Int-1	No
9	22	RA	46, XY[25]	Int-1	No
10	7	RA	46, XX[31]	Int-1	No
11	22	RA	46, XX[22]	Int-1	No
12	32	RA	46, XY[28]	Int-1	No
13	9	RA	46, XX, del(12)(p12)[5]/46, XX[15]	Int-1	No
14	36	RA	46, XX[23]	Int-1	No
15	43	RA	46, XX[25]	Int-1	No
16	23	RA	46, XX[30]	Int-1	No
17	32	RA	46, XY, del(6)(q21)[3]/46, XY[21]	Int-1	No
18	31	RA	46, XY, del(17)(p12)[6]/46, XY[24]	Int-1	No
19	51	RA	46, XY, del(17)(p12)[8]/46, XY[20]	Int-1	No
20	14	RA	46, XY, del(17)(p12)[13]/46, XY[36]	Int-1	No
21	15	RA	46, XY, del(17)(p12)[4]/46, XY[18]	Int-1	No
22	37	RA	46, XX[30]	Int-1	No
23	16	RA	51, XX, +4, +6, +8, +14, +20[3]/46, XX[41]	Int-1	No
24	12	RA	46, XY, del(17)(p12)[4]/46, XY[17]	Int-1	No
25	16	RA	46, XX, inv(3)(q21q26)[5]/46, XX[15]	Int-1	No
26	84	RA	46, XY, del(17)(p12)[4]/46, XY[16]	Int-1	No
27	19	RA	46, XY[32]	Int-1	No
28	29	RA	46, XY, del(17)(p12)[6]/46, XY[19]	Int-1	No
29	62	RA	46, XX[29]	Int-1	No
30	18	RA	46, XY, del(1)(q32)[8]/46, XY[16]	Int-1	No
31	51	RA	46, XY, del(11)(q23)[8]/46, XY[17]	Int-1	No
32	30	RA	46, XX, del(17)(p12)[5]/46, XX[16]	Int-1	No
33	31	RA	46, XY, del(11)(q23)[4]/46, XY[17]	Int-1	No
34	13	RA	46, XY, del(7)(q22)[7]/46, XX[14]	Int-2	Yes/6
35	13	RA	46, XY, del(12)(p12)[4]/46, XY[36]	Int-1	No
36	49	RA	46, XX[20]	Int-1	No
37	9	RA	46, XY, del(3)(q23)[4]/46, XY[13]	Int-1	No
38	10	RA	46, XX[34]	Int-1	No
39	42	RA	46, XY, del(17)(p12)[6]/46, XY[16]	Int-1	No
40	32	RA	46, XY[27]	Int-1	No
41	48	RA	46, XY[20]	Int-1	No
42	41	RA	46, XX[20]	Int-1	No
43	56	RA	46, XX[22]	Int-1	No
44	34	RA	46, XY[22]	Int-1	No
45	10	RA	46, XY, del(17)(p12)[5]/46, XY[16]	Int-1	No
46	24	RA	46, XX, del(17)(p12)[3]/46, XX[20]	Int-1	No
47	19	RA	46, XY[30]	Int-1	No
48	29	RA	46, XX[34]	Int-1	No
49	11	RA	46, XY[20]	Int-1	No
50	4	RA	47, XY, +mar[3]/46, XY[25]	Int-1	No
51	38	RA	46, XX[20]	Int-1	No
52	26	RA	46, XX[42]	Int-1	No
53	27	RA	46, XX[20]	Int-1	No
54	7	RA	46, XY, del(12)(p12)[3]/46, XX[27]	Int-1	No
55	13	RA	46, XY, del(17)(p12)[9]/46, XY, del(17)(p12), del(12)(p13)[5]/46, XY, del(11)(q23)[3]/46, XY[34]	Int-1	No
56	45	RA	46, XX[20]	Int-1	No
57	18	RA	46, XX, del(9)(p21)[4]/46, XX[17]	Int-1	No
58	44	RA	46, XY[22]	Int-1	No
59	48	RA	46, XX, del(5)(q13q33)[7]/46, XX[13]	Int-1	No
60	32	RA	46, XY[30]	Int-1	No
61	72	RA	46, XX[21]	Int-1	No
62	56	RA	46, XX[30]	Int-1	No
63	42	RA	46, XY[32]	Int-1	No
64	7	RA	46, XY, del(11)(q23)[4]/46, XY[48]	Int-1	No
65	2	RA	46, XX, del(4)(q22)[4]/46, XX[28]	Int-1	No
66	14	RA	46, XY[50]	Int-1	No
67	61	RA	46, XX, del(5)(q13q33)[6]/46, XX[21]	Int-1	No
68	36	RA	46, XY[22]	Int-1	No
69	12	RA	46, XY[30]	Int-1	No
70	29	RA	46, XX[21]	Int-1	No
71	11	RA	46, XX[36]	Int-1	No
72	52	RA	46, XY[25]	Int-1	No
73	58	RA	46, XX, del(5)(q13q33)[16]/46, XX[7]	Int-1	No
74	36	RA	46, XY[28]	Int-1	No
75	12	RA	46, XY[30]	Int-1	No
76	49	RA	46, XY[27]	Int-1	No
77	10	RA	45, XY, −7[16]/46, XY[6]	Int-2	Yes/4
78	13	RA	45, XY, −7[8]/46, XY[12]	Int-2	No
79	37	RA	46, XX[24]	Int-1	No
80	10	RA	46, XX, del(6)(q24)[3]/46, XX[15]	Int-1	No
81	17	RA	46, XX[20]	Int-1	No
82	11	RAEB	46, XY, del(11)(q23)[7]/46, XY[13]	Int-2	Yes/4.5
83	6	RAEB	46, XX, i(9)(q10)[15]/46, XX[7]	Int-2	Yes/1
84	56	RAEB	46, XX, dup(1)(q12)[18]/45, XX, dup(1); (q12), del(3)(q23), −5[3]/46, XX[42]	Int-2	Yes/2
85	44	RAEB	46, XX, del(17)(p12)[8]/46, XX[14]	Int-2	No
86	63	RAEB	46, XX, del(17)(p12)[5]/46, XX[45]	Int-2	No
87	58	RAEB	46, XY, del(20)(q11)[29]/46, XY[2]	Int-2	No
88	17	RAEB	46, XY, del(11)(q23)[9]/46, XY[13]	Int-2	Yes/4
89	45	RAEB	46, XY, del(17)(p12)[8]/46, XY[14]	Int-2	No
90	41	RAEB	46, XY, del(11)(q23)[8]/46, XY[16]	Int-2	No
91	15	RAEB	46, XX, del(11)(q23)[8]/46, XX[16]	Int-2	Yes/3
92	42	RAEB	46, XX, del(5)(q21), del(8)(q22)[14]/46, XX, del(5)(q21), del(8)(q22), i(9)(q10)[9]	High	Yes/1
93	60	RAEB	47, XY, +8[32]/46, XY[23]	Int-2	Yes/2.5
94	58	RAEB	46, XX, t(7; 9)(q32; q34)[3]/46, XX[29]	High	Yes/3
95	19	RAEB	46, XX, i(7)(q10)[4]/46, XX[17]	High	Yes/1
96	61	RAEB	46, XX, del(6)(q21)[13]/46, XX[9]	Int-2	Yes/2
97	58	RAEB	45, XY, del(7)(q22)[16]/46, XY[5]	High	Yes/3
98	11	RAEB	45, XY, −7[25]/46, XY[3]	High	Yes/1
99	49	RAEB	47, XY, +6[8]/46, XX[20]	Int-2	No
100	55	RAEB	45, XX, −5[6]/46, XX[18]	Int-2	No
101	1	RAEB-t	45, XX, −7[24]/46, XX[2]	High	Yes/1
102	42	RAEB-t	46, XY, del(6)(q21)[5]/46, XY[18]	High	Yes/5
103	64	RAEB-t	46, XY, t(1; 6)(p23; p25)[16]/46, XY, t(1; 6); (p23; p25), del(7)(p25), i(9)(q10)[2]/46, XY[11]	High	Yes/1
104	57	RAEB-t	47, XY, +8[14]/46, XY[8]	High	Yes/2
105	7	RAEB-t	46, XY, del(11)(q23)[12]/46, XY[13]	High	Yes/3.5