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BioMed Research International
Volume 2014 (2014), Article ID 563131, 17 pages
Review Article

Development of a Promising Fish Model (Oryzias melastigma) for Assessing Multiple Responses to Stresses in the Marine Environment

Key Lab of Urban Environment and Health, Institute of Urban Environment, Chinese Academy of Sciences, Number 1799 Jimei Street, Xiamen 361021, China

Received 5 November 2013; Revised 8 January 2014; Accepted 23 January 2014; Published 3 March 2014

Academic Editor: Zhi-Hua Li

Copyright © 2014 Sijun Dong et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


With the increasing number of contaminants in the marine environment, various experimental organisms have been “taken into labs” by investigators to find the most suitable environmentally relevant models for toxicity testing. The marine medaka, Oryzias melastigma, has a number of advantages that make it a prime candidate for these tests. Recently, many studies have been conducted on marine medaka, especially in terms of their physiological, biochemical, and molecular responses after exposure to contaminants and other environmental stressors. This review provides a literature survey highlighting the steady increase of ecotoxicological research on marine medaka, summarizes the advantages of using O. melastigma as a tool for toxicological research, and promotes the utilization of this organism in future studies.