Review Article

Synergistic Effects of Toxic Elements on Heat Shock Proteins

Table 1

Biomarkers proposed for environmental risk assessment.

Name of biomarkerReference

Esterases [130]
Polytene chromosomes of chironomids (Diptera)[131]
HSP60, HSP70, alpha B-crystallin homologue, lipid peroxide, total glutathione level, ubiquitin, mitochondrial manganese superoxide dismutase, metallothionein, and cytochrome P450 2E homologue[93, 122, 123]
Numbers of macrophages in liver tissue, changes in various blood parameters[105]
Histological and ultrastructural markers, lysosomal membrane stability of coelomocytes, histidine[51, 132]
Catalase activity[78]
Metabonomics analysis using NMR techniques [133]
P-glycoprotein, major vault protein, topoisomerase-II[103]
Acetylcholinesterase inhibition and imposex [134]
Digestive enzymes, glycolytic enzymes, and cellular energy allocation[124]
Apoptosis in marine sponges and spiders[135, 136]