Meta-Analysis of Low Density Lipoprotein Receptor (<i>LDLR</i>) rs2228671 Polymorphism and Coronary Heart Disease

<table class="table-group" id="tab3"><tr><td><table class="table"><tr><td class="thead-hr" colspan="9"><hr/></td></tr><tr class="thead"><td align="left">Gender</td><td align="center">Group</td><td align="center">CC/CT/TT</td><td align="center"><span style="width: 16.35px;"><svg height="20.5625" id="M22" style="vertical-align:-2.53308pt" version="1.1" viewbox="0 0 16.35 20.5625" width="16.35" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
<g transform="matrix(.017,-0,0,-.017,.062,15.775)"><path d="M565 434q-29 -30 -107.5 -131t-125.5 -168q22 -126 55 -265q8 -35 12.5 -45.5t11.5 -10.5q26 0 76 59l23 -23q-77 -111 -134 -111q-42 0 -63 96l-43 222q-148 -211 -219 -335h-10q-30 45 9 103l209 291q-27 155 -42 214q-7 27 -11.5 35.5t-12.5 8.5q-19 0 -62 -57l-21 21
q73 110 126 110q18 0 31.5 -22.5t19.5 -52.5l35 -184l160 234l74 25z" id="x1D712"></path></g>
<g transform="matrix(.012,-0,0,-.012,9.95,7.613)"><path d="M412 140l28 -9q0 -2 -35 -131h-373v23q112 112 161 170q59 70 92 127t33 115q0 63 -31 98t-86 35q-75 0 -137 -93l-22 20l57 81q55 59 135 59q69 0 118.5 -46.5t49.5 -122.5q0 -62 -29.5 -114t-102.5 -130l-141 -149h186q42 0 58.5 10.5t38.5 56.5z" id="x32"></path></g>
</svg></span></td><td align="center"><svg height="11.175" id="M23" style="vertical-align:-0.0pt" version="1.1" viewbox="0 0 10.9375 11.175" width="10.9375" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
<g transform="matrix(.017,-0,0,-.017,.062,11.113)"><path d="M619 482q0 -69 -40.5 -119t-96 -72.5t-118.5 -26.5h-44l-70 20l-31 -151q-14 -67 0.5 -83t89.5 -22l-5 -28h-287l8 28q65 7 81.5 22t29.5 83l79 398q12 56 0.5 70.5t-78.5 20.5l7 28h255q108 0 164 -43t56 -125zM524 478q0 141 -146 141q-25 0 -47 -8q-16 -6 -20.5 -13.5
t-10.5 -39.5l-43 -241q37 -13 83 -13q67 0 125.5 45t58.5 129z" id="x1D443"></path></g>
</svg> (df = 2)</td><td align="center">C/T</td><td align="center"><span style="width: 16.35px;"><svg height="20.5625" id="M24" style="vertical-align:-2.53308pt" version="1.1" viewbox="0 0 16.35 20.5625" width="16.35" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
<g transform="matrix(.017,-0,0,-.017,.062,15.775)"><path d="M565 434q-29 -30 -107.5 -131t-125.5 -168q22 -126 55 -265q8 -35 12.5 -45.5t11.5 -10.5q26 0 76 59l23 -23q-77 -111 -134 -111q-42 0 -63 96l-43 222q-148 -211 -219 -335h-10q-30 45 9 103l209 291q-27 155 -42 214q-7 27 -11.5 35.5t-12.5 8.5q-19 0 -62 -57l-21 21
q73 110 126 110q18 0 31.5 -22.5t19.5 -52.5l35 -184l160 234l74 25z" id="x1D712"></path></g>
<g transform="matrix(.012,-0,0,-.012,9.95,7.613)"><path d="M412 140l28 -9q0 -2 -35 -131h-373v23q112 112 161 170q59 70 92 127t33 115q0 63 -31 98t-86 35q-75 0 -137 -93l-22 20l57 81q55 59 135 59q69 0 118.5 -46.5t49.5 -122.5q0 -62 -29.5 -114t-102.5 -130l-141 -149h186q42 0 58.5 10.5t38.5 56.5z" id="x32"></path></g>
</svg></span></td><td align="center"><svg height="11.175" id="M25" style="vertical-align:-0.0pt" version="1.1" viewbox="0 0 10.9375 11.175" width="10.9375" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
<g transform="matrix(.017,-0,0,-.017,.062,11.113)"><path d="M619 482q0 -69 -40.5 -119t-96 -72.5t-118.5 -26.5h-44l-70 20l-31 -151q-14 -67 0.5 -83t89.5 -22l-5 -28h-287l8 28q65 7 81.5 22t29.5 83l79 398q12 56 0.5 70.5t-78.5 20.5l7 28h255q108 0 164 -43t56 -125zM524 478q0 141 -146 141q-25 0 -47 -8q-16 -6 -20.5 -13.5
t-10.5 -39.5l-43 -241q37 -13 83 -13q67 0 125.5 45t58.5 129z" id="x1D443"></path></g>
</svg> (df = 1)</td><td align="center">OR (95% CI)</td></tr><tr><td class="thead-hr" colspan="9"><hr/></td></tr><tr><td align="left" rowspan="2">European population</td><td align="center">Cases </td><td align="center">6218/1251/57</td><td align="center" rowspan="2">20.59</td><td align="center" rowspan="2">&lt;.0001</td><td align="center">13687/1365</td><td align="center" rowspan="2">20.26</td><td align="center" rowspan="2">&lt;.0001</td><td align="center" rowspan="2">1.180 (1.098–1.269)</td></tr><tr><td align="center">Controls </td><td align="center">7685/1808/107</td><td align="center">17178/2022</td></tr><tr class="table-tr"><td colspan="9"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

Genotype and allele frequency distributionof<i> LDLR</i> gene rs2228671 polymorphism in European population. 

BioMed Research International

tab3

Table 3

Table 3: Meta-Analysis of Low Density Lipoprotein Receptor (<i>LDLR</i>) rs2228671 Polymorphism and Coronary Heart Disease 

BioMed Research International

Meta-Analysis of Low Density Lipoprotein Receptor (LDLR) rs2228671 Polymorphism and Coronary Heart Disease

Table 3