Research Article

Variability in Myosteatosis and Insulin Resistance Induced by High-Fat Diet in Mouse Skeletal Muscles

Table 1

Body mass, muscle mass, and glycometabolic parameters in control mice and high-fat diet (HFD) mice after 12 weeks of dietary manipulation.

VariableControl mice ()HFD mice () value

Body weight increase (g)8.5 ± 1.617.2 ± 4.6
Tibialis anterior weight (% body weight)0.55 ± 0.050.48 ± 0.060.021
Soleus weight (% body weight)0.067 ± 0.0090.051 ± 0.0070.002
Plasma glucose (mg/dL)73 ± 19120 ± 210.008
Plasma insulin (mg/mL)85.8 ± 5.3106.0 ± 12.60.016
Plasma total cholesterol (mg/dL)77.2 ± 5.7129.8 ± 26.30.008
Plasma triglycerides (mg/dL)32.8 ± 7.877.0 ± 33.50.017