Serum Osteopontin Level Correlates with Carotid-Femoral Pulse Wave Velocity in Geriatric Persons

Table 4

Multivariable stepwise linear regression analysis of carotid-femoral pulse wave velocity among 93 geriatric adults.

Items	Beta	𝑅^2 change	Regression coefficient (95% confidence interval)	P value
Log-OPN (pg/mL)	0.233	0.123	1.868 (0.444 to 3.291)	0.011^∗
Body mass index (kg/m^2)	0.333	0.093	0.243 (0.119 to −0.367)	<0.001^∗
Creatinine (mg/dL)	0.195	0.074	1.517 (0.123 to 2.911)	0.033^∗
Age (years)	0.250	0.047	0.130 (0.037 to 0.223)	0.007^∗
Diabetes	0.195	0.035	1.090 (0.108 to 2.072)	0.030^∗

Data of osteopontin levels showed skewed distribution and therefore were log-transformed before analysis.
^∗𝑃<0.05 was considered statistically significant in the multivariable stepwise linear regression analysis (adopted factors: diabetes, dyslipidemia, age, waist circumference, body mass index, systolic blood pressure, diastolic blood pressure, pulse pressure, HDL-C, creatinine, GFR, and log-OPN).
HDL-C, high-density lipoprotein cholesterol; GFR, glomerular filtration rate; OPN, osteopontin.