The Influence of Ionizing Radiation, Temperature, and Light on Eplerenone in the Solid State

Table 3

Eplerenone and impurities of known structure in degraded and nondegraded samples.

Conditions	Content [%]
	Eplerenone (10.23 min)	Imp. D (7.07 min)	Imp. A (7.47 min)	Imp. B (12.83 min)	Imp. F (15.15 min)
Nondegraded	99.782	—	—	—	0.044
6 mln lux h	99.657	—	0.008	—	0.031
90°C RH 0%	99.598	—	0.007	—	0.022
60°C RH 76.4%	99.737	—	0.007	—	0.051
25 kGy	99.772	0.040	—	—	—
50 kGy	99.559	0.070	—	—	—
100 kGy	99.329	0.118	—	0.017	—
200 kGy	98.758	0.204	—	0.032	—
400 kGy	98.006	0.354	—	0.050	—