BioMed Research International / 2014 / Article / Tab 4

Research Article

The Influence of Ionizing Radiation, Temperature, and Light on Eplerenone in the Solid State

Table 4

Eplerenone and impurities of unknown structure in degraded and nondegraded samples.

ConditionsRecovery* [%]
a
3.57 min
b
3.79 min
c
4.40 min
d
4.64 min
e
5.15 min
f
5.49 min
g
5.87 min
h
6.48 min
i
8.03 min
j
8.83 min
k
9.17 min
l
16.64 min
m
17.89 min
n
19.71 min

Nondegraded0.0150.0120.0300.0240.0360.0310.010.018
6 mln lux h0.0130.0140.1120.0330.0270.0350.0210.0380.0090.021
90°C RH 0%0.0100.0140.0090.0340.0280.0350.1390.0170.0110.023
60°C RH 76.4%0.0120.0130.0090.0700.0250.0350.0170.025
25 kGy0.0220.0110.0380.0110.0120.0190.0350.021
50 kGy0.0220.0100.0630.0550.0370.0300.1040.019
100 kGy0.0260.0180.0210.0930.1060.0240.0210.183
200 kGy0.0340.0330.0370.0220.0170.1460.1870.0560.0250.338
400 kGy0.0490.0630.0640.0330.0210.2490.3650.0650.0260.557

Content of unknown impurities calculated for their relative response factor equal to that of eplerenone.