Research Article

Cellular Levels of Oxidative Stress Affect the Response of Cervical Cancer Cells to Chemotherapeutic Agents

Figure 1

SiHa cells are more resistant than CaSki cells to treatment with the chemotherapeutic drugs DOX (a and c) and cisplatin (b and d). (a and b) SiHa and CaSki cells (1.5 × 104 cells per well) were seeded into a 96-well plate, allowed to incubate overnight, and then treated with the indicated concentrations of drugs for 20 h. (c and d) SiHa and CaSki cells (0.5 × 104 cells per well) were seeded into a 96-well plate, allowed to incubate overnight, and then treated with the indicated concentrations of drugs for 72 h. Viability was measured by crystal violet and the viability of untreated cells was set at 100%. Each measurement was done in triplicate and error bars indicate the standard deviations of the means.
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