Oral and Intraperitoneal Administration of Quercetin Decreased Lymphocyte DNA Damage and Plasma Lipid Peroxidation Induced by TSA In Vivo
Figure 4
Lymphocyte DNA damage (a) and lipid peroxidation (TBARS level) (b) in tumor-bearing mice with various treatments. Thirty-six male nude mice were injected with A549 cells and after 3 weeks were treated with TSA alone (0.5 mg/kg body weight) or in combination with quercetin (OL and OH, quercetin administered orally at 20 and 100 mg/kg body weight, resp.; IL and IH, quercetin administered intraperitoneally at 2 and 10 mg/kg body weight, resp.) for 16 weeks as described in Section 2. The control group was administered the vehicle only. Values (means ± SD, ) not sharing a common letter are significantly different ().
