Research Article

Depletion of Arginine by Recombinant Arginine Deiminase Induces nNOS-Activated Neurotoxicity in Neuroblastoma Cells

Table 2

Vinyl-L-NIO triggered cytotoxicity in the presence of NMDA.

Cell viabilityControlVinyl-L-NIOVinyl-L-NIO + NMDA

% of control100 ± 3.598.4 ± 3.486.7 ± 1.2*

The combination of 5  M vinyl-L-NIO and 1 mM NMDA caused cytotoxicity compared to the control and vinyl-L-NIO alone groups with statistical significance of .