Research Article

Large-Scale Protein-Protein Interactions Detection by Integrating Big Biosensing Data with Computational Model

Table 1

Division of amino acids into seven groups based on the dipoles and volumes of the side chains.

Group Class Dipole scaleVolume scale

1Ala, Gly, ValDipole < 1.0Volume < 50
2Ile, Leu, Phe, ProDipole < 1.0Volume > 50
3Tyr, Met, Thr, Ser1.0 < dipole < 2.0Volume > 50
4His, Asn, Gln, Trp2.0 < dipole < 3.0Volume > 50
5Arg, LysDipole > 3.0Volume > 50
6Asp, GluDipole > 3.0
(opposite orientation)
Volume > 50
7 Cys1.0 < dipole < 2.0
(form disulphide bonds)
Volume > 50