Profiling of Biomarkers for the Exposure of Polycyclic Aromatic Hydrocarbons: Lamin-A/C Isoform 3, Poly[ADP-ribose] Polymerase 1, and Mitochondria Copy Number Are Identified as Universal Biomarkers
Figure 6
Confirmation of PARP-1 and LMNA biomarkers using Western blot. The expression of PARP-1 was remarkably increased after exposure of BaP, pentacene, and fluoranthene (100 M concentration). LMNA protein was highly expressed after BaP exposure. Normal, no treatment group; DMSO, only DMSO (0.1%) treated group; K, kilodalton.