Research Article

Subchondral Bone Plate Thickening Precedes Chondrocyte Apoptosis and Cartilage Degradation in Spontaneous Animal Models of Osteoarthritis

Table 2

Correlation between chondrocyte apoptosis and both cartilage degradation and Sb parameters.

Caspase-3

Microscopic score0.4<0.01
BMD Sbp0.2<0.05
BMD Tb0.1<0.05
SbpTh0.2<0.05
BV/TV0.1>0.05
Tb.Th0.1>0.05
Tb.N0.02>0.05
Tb.Sp0.1>0.05
Tb.Pf−0.02>0.05