A Pilot Study Evaluating the Contribution of SLC19A1 (RFC-1) 80G>A Polymorphism to Alzheimer’s Disease in Italian Caucasians

Table 1

Demographic characteristics of the study population and data on plasma total homocysteine and serum folate and vitamin B12 levels.

	𝑛	Males 𝑛 (%)	Females 𝑛 (%)	Age; (years, mean ± SD)	t-hcy^a (𝜇mol/L, mean ± SEM)	Folate^a (ng/mL, mean ± SEM)	Vitamin B12^a (pg/mL, mean ± SEM)
AD	192	65 (33.8%)	127 (66.2%)	76.4±7.3	21.2±1.7	7.1±0.8^b	407.8±25.2
Controls	186	72 (38.7%)	114 (61.3%)	73.5±6.4	14.6±0.7	8.2±1.0	437.9±30.9

aAvailable from 104 AD and 64 controls.
^bSignificant difference versus controls (𝑃 value obtained with analysis of covariance using log transformed data and corrected for age and gender).