Anti-Inflammatory Effects of the Nicotinergic Peptides SLURP-1 and SLURP-2 on Human Intestinal Epithelial Cells and Immunocytes
Figure 2
Anti-inflammatory effects of rSLURP-1 and -2 on immunocytes. The anti-inflammatory effects of rSLURP-1 (S1) and -2 (S2), 0.01 μg/mL, on production of proinflammatory cytokines and IL-10 by the CEM stimulated with 10 μM PHA (a) and by the differentiated U937 macrophages stimulated with 200 ng/mL LPS (b) incubated for 16 h in a humid, 5% CO2 incubator at a cell density of 1 × 106 cells/well were measured by QIA, as detailed in Materials and Methods. Each experiment was performed in triplicate. Asterisk = , compared to intact cells. Pound sign = , compared to PHA or LPS given alone.
