Nitric Oxide and Superoxide Anion Balance in Rats Exposed to Chronic and Long Term Intermittent Hypoxia

Figure 4

Immunohistochemical detection of p22phox positive cells in the adventitia of pulmonary arteries from rats exposed to normoxia (NX, 𝑛=10), intermittent hypoxia (CIH2x2, 𝑛=10), or chronic hypoxia (CH, 𝑛=10). (a) Representative examples of projections obtained from confocal microscopy images (×40 zoom 4). (b) Quantitative analysis; 𝑛 represents the number of animals; *𝑃<0.05 compared to NX.

(a)

(b) p22phox positive cells