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BioMed Research International
Volume 2014, Article ID 610623, 11 pages
Review Article

Anterior Segment Optical Coherence Tomography Imaging of Conjunctival Filtering Blebs after Glaucoma Surgery

1Ophthalmology Unit, Department of Neurological, Neuropsychological, Morphological and Movement Sciences, University of Verona, 53593 Verona, Italy
2Ophthalmic Clinic, Department of Medicine and Aging Science, Ophthalmic Clinic, University G. d’Annunzio of Chieti-Pescara, Via dei Frentani 114, 66100 Chieti, Italy
3Excellence Eye Research Center, CeSI, G. d’Annunzio University of Chieti-Pescara, 66100 Chieti, Italy
4Ophthalmic Clinic, Department of Surgical Science, University of L’Aquila, 67100 L’Aquila, Italy

Received 23 May 2014; Accepted 25 June 2014; Published 20 July 2014

Academic Editor: Ciro Costagliola

Copyright © 2014 Rodolfo Mastropasqua et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Time domain (TD) and spectral domain (SD) optical coherence tomography (OCT) are cross-sectional, noncontact, high-resolution diagnostic modalities for posterior and anterior segment (AS) imaging. The AS-OCT provides tomographic imaging of the cornea, iris, lens, and anterior chamber (AC) angle in several ophthalmic diseases. In glaucoma, AS-OCT is utilized to evaluate the morphology of AS structures involved in the pathogenesis of the disease, to obtain morphometric measures of the AC, to evaluate the suitability for laser or surgical approaches, and to assess modifications after treatment. In patients undergoing surgery, AS-OCT is crucial in the evaluation of the filtering bleb functionality, permitting a combined qualitative and quantitative analysis. In this field, AS-OCT may help clinicians in distinguishing between functioning and nonfunctioning blebs by classifying their macroscopic morphology, describing bleb-wall features, bleb cavity, and scleral opening. This information is critical in recognizing signs of filtration failure earlier than the clinical approach and in planning the appropriate timing for management procedures in failing blebs. In this review, we summarize the applications of AS-OCT in the conjunctival bleb assessment.