Impact of Blood Type, Functional Polymorphism (T-1676C) of the COX-1 Gene Promoter and Clinical Factors on the Development of Peptic Ulcer during Cardiovascular Prophylaxis with Low-Dose Aspirin

Table 2

Blood group and COX-1 genotype in low-dose aspirin users with and without peptic ulcer.

	Gastritis/normal	Peptic ulcer	value
Blood type			0.047
A	36 (33.0%)	29 (26.1%)
B	38 (34.9%)	25 (22.5%)
O	32 (29.4%)	51 (45.9%)
AB	5 (4.6%)	6 (5.4%)
COX-1 genotype*			0.245
T/T	15 (19.5%)	22 (24.7%)
C/T	59 (76.6%)	59 (66.3%)
C/C	3 (3.9%)	8 (9.0%)

One hundred and eighty six DNA samples were available.