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BioMed Research International
Volume 2014, Article ID 616025, 9 pages
http://dx.doi.org/10.1155/2014/616025
Research Article

Estrogen-Related Receptor Alpha Confers Methotrexate Resistance via Attenuation of Reactive Oxygen Species Production and P53 Mediated Apoptosis in Osteosarcoma Cells

1First School of Clinical Medicine, Guangzhou University of Chinese Medicine, Guangzhou 510405, China
2Cancer Center, University of California, Davis, Sacramento, CA 95817, USA
3State Key Hip Joints Center, First Affiliated Hospital of Guangzhou University of Chinese Medicine, No. 12 Jichang Road, Guangzhou, Guangdong 510405, China

Received 26 March 2014; Accepted 25 April 2014; Published 19 May 2014

Academic Editor: Jianzhen Xu

Copyright © 2014 Peng Chen et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [7 citations]

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  • Xiaoming Zhu, Yang Yang, Tao Han, Guowu Yin, Ping Gao, Yunfeng Ni, Xiaohua Su, Yuying Liu, and Yuanqing Yao, “Suppression of microRNA-18a expression inhibits invasion and promotes apoptosis of human trophoblast cells by targeting the estrogen receptor alpha ge,” Molecular Medicine Reports, vol. 12, no. 2, pp. 2701–2706, 2015. View at Publisher · View at Google Scholar
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