Research Article

Preventive Effects of Dexmedetomidine on the Liver in a Rat Model of Acid-Induced Acute Lung Injury

Table 1

Arterial blood gas data at the end of the experiment (median ± interquartile range).

Arterial blood gas
GroupsPhPaO2 (mmHg)PaCO2 (mmHg)

Group 17.38 ± 0.0787.0 ± 9.040.0 ± 5.0
Group 27.39 ± 0.0690.0 ± 5.040.0 ± 8.0
Group 37.30 ± 0.06a,b72.0 ± 10.0a,b51.0 ± 5.0a,b
Group 47.37 ± 0.06c 83.0.0 ± 9.0c44.0 ± 5.0c

value between 4 groups (with Kruskal-Wallis one-way analysis of variance)

Groups 1–40.004<0.0010.001

Group 1: normal saline group; Group 2: normal saline plus ventilator (V) group; Group 3: hydrochloric acid (HCl) plus ventilator group; Group 4: HCl + V plus dexmedetomidine group.
values of pairwise comparisons (with Mann-Whitney test):
aCompared with group 1 ()
bCompared with group 2 ()
cCompared with group 3 ().