Preventive Effects of Dexmedetomidine on the Liver in a Rat Model of Acid-Induced Acute Lung Injury

Table 4

The histopathologic injury scores of liver and CD68-VEGF levels in rats according to groups.

Groups	Total injury score	CD68	VEGF
Group 1	0.0 ± 0.0	1.0 ± 1	3.0 ± 1
Group 2	0.0 ± 0.0	1.0 ± 1	2.0 ± 1
Group 3	12.0 ± 7^a	3.0 ± 1^c	1.0 ± 1^e
Group 4	4.0 ± 1^b	1.0 ± 1^d	2.0 ± 1^f
value between 4 groups (with Kruskal-Wallis one-way analysis of variance)
Groups 1–4	<0.001	0.005	0.001

Group 1: normal saline group; Group 2: normal saline plus ventilator (V) group; Group 3: hydrochloric acid (HCl) plus ventilator group; Group 4:
HCl + V plus dexmedetomidine group.
Values are median ± interquartile range.
Mann-Whitney test results are as follows.
^a Different from group 1 ().
^b Different from group 3 ().
^c Different from group 1 ().
^d Different from group 3 ().
^e Different from group 1 ().
^f Different from group 3 ().