The Chromosome 9p21 Variant Not Predicting Long-Term Cardiovascular Mortality in Chinese with Established Coronary Artery Disease: An Eleven-Year Follow-Up Study
Table 3
Baseline characteristics of the subjects with coronary artery disease (CAD) according to the rs4977574 genotypes.
GG ()
GA ()
AA ()
Age (year)
66 ± 10a
68 ± 10b
68 ± 10b
0.009
Male, (%)
193 (77.8%)
385 (80.4%)
164 (82.8%)
0.416
BMI (kg/m2)
25.7 ± 3.4
25.1 ± 3.3
25.2 ± 3.3
0.191
Systolic BP (mmHg)
127 ± 12
125 ± 13
127 ± 13
0.062
Diastolic BP (mmHg)
72 ± 10
71 ± 10
70 ± 10
0.264
Current smoking, (%)
75 (30.2%)
132 (27.6%)
53 (26.8%)
0.668
Hypertension, (%)
170 (68.5%)
297 (62.0%)
127 (64.1%)
0.218
Diabetes mellitus, (%)
126 (50.8%)
228 (47.6%)
92 (46.5%)
0.612
Previous MI
26 (10.5%)
45 (9.4%)
21 (10.6%)
0.844
Statins treatment
11 (4.4%)
35 (7.3%)
15 (7.6%)
0.275
Triglyceride (mmol/L)
1.7 ± 1.4
1.5 ± 1.0
1.6 ± 1.6
0.237
Total cholesterol (mmol/L)
4.7 ± 1.2
4.7 ± 1.1
4.8 ± 1.3
0.520
HDL cholesterol (mmol/L)
1.1 ± 0.3
1.2 ± 0.3
1.1 ± 0.3
0.198
LDL cholesterol (mmol/L)
2.8 ± 0.9
2.9 ± 1.0
3.0 ± 1.1
0.275
Fasting glucose (mmol/L)
6.8 ± 2.7
6.9 ± 2.7
6.7 ± 2.7
0.780
Gensini score*
21.5 (8.0, 48.8)
20.0 (8.0, 48.0)
20.0 (6.4, 41.3)
0.412
Significant difference between a and b.
*Data of Gensini score presented as median (interquartile range). BMI: body mass index, BP: blood pressure, HDL: high-density lipoprotein, LDL: low-density lipoprotein, and MI: myocardial infarction.
