The Chromosome 9p21 Variant Not Predicting Long-Term Cardiovascular Mortality in Chinese with Established Coronary Artery Disease: An Eleven-Year Follow-Up Study

Table 4

Cox regression models for the effects of rs4977574 in patients with CAD at baseline.

(a) Cardiovascular mortality

	Dominant model			Recessive model
	HR	(95% CI)	𝑃	HR	(95% CI)	𝑃
Age (10 years)	1.80	(1.55, 2.09)	<0.001	1.79	(1.54, 2.08)	<0.001
Male	1.05	(0.78, 1.41)	0.741	1.05	(0.78, 1.41)	0.755
Current smoking	0.90	(0.68, 1.20)	0.474	0.91	(0.68, 1.20)	0.498
Hypertension	0.91	(0.71, 1.160)	0.456	0.91	(0.71, 1.16)	0.444
Diabetes mellitus	1.84	(1.46, 2.33)	<0.001	1.84	(1.46, 2.34)	<0.001
Previous MI	1.20	(0.83, 1.72)	0.336	1.20	(0.84, 1.74)	0.318
Statins treatment	0.75	(0.44, 1.28)	0.285	0.75	(0.44, 1.28)	0.289
G allele	1.25	(0.93, 1.68)	0.138	1.05	(0.80, 1.37)	0.729

MI: myocardial infarction.

(b) Total mortality

	Dominant model			Recessive model
	HR	(95% CI)	𝑃	HR	(95% CI)	𝑃
Age (10 years)	2.12	(1.89, 2.39)	<0.001	2.12	(1.89, 2.39)	<0.001
Male	1.26	(1.00, 1.60)	0.052	1.27	(1.00, 1.60)	0.051
Current smoking	1.01	(0.82, 1.24)	0.937	1.01	(0.82, 1.24)	0.941
Hypertension	0.91	(0.75, 1.09)	0.305	0.90	(0.75, 1.08)	0.271
Diabetes mellitus	1.55	(1.30, 1.84)	<0.001	1.54	(1.30, 1.84)	<0.001
Previous MI	1.19	(0.90, 1.57)	0.226	1.19	(0.90, 1.57)	0.230
Statins treatment	0.76	(0.51, 1.14)	0.188	0.77	(0.51, 1.15)	0.202
G allele	1.18	(0.95, 1.47)	0.135	1.11	(0.91, 1.35)	0.312

MI: myocardial infarction.