Effects of Hypertension and Exercise on Cardiac Proteome Remodelling

Figure 1

Pathologic and physiologic cardiac hypertrophy. Figure 1 sums the factors associated with hypertension pathogenesis and its effect on some target organs (e.g., brain, kidney, and arterioles: highlighted) and cardiovascular system. Moreover, differences in cardiac hypertrophy, heart transversal session, and cardiomyocyte are presented between pathologic and physiologic hypertrophy, followed by distinct physiologic and molecular regulations. Distinct molecular regulation between pathologic and physiologic cardiac hypertrophy is associated with the development of cardiac dysfunction* or cardiac improvement**.