E-Cadherin and Gastric Cancer: Cause, Consequence, and Applications
Figure 2
E-cadherin regulated signaling pathways involved in gastric cancer, including Wnt/β-catenin pathway, Rho GTPases, NF-κB pathway, EGFR, and Rac-MAPK signaling. Activation of these pathways leads to increase in cell proliferation, decrease in cell apoptosis, cell migration, and inflammation associated gastric cancer development.
