Research Article

HS1,2 Ig Enhancer Alleles Association to AIDS Progression in a Pediatric Cohort Infected with a Monophyletic HIV-Strain

Figure 1

Schematic map of the constant heavy chain region: (a) location of the two regulatory regions within the heavy chain genes on chromosome 14q32; (b) enlargement of the 3′RR-1 hs1.2 polymorphic enhancer and schematic representation of the four alleles; (c) nucleotidic sequence of the hs1.2 enhancer with the differences of the four alleles and the consensus for the Sp1 and NF-kB transcription factor consensus.
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