Mas-Mediated Antioxidant Effects Restore the Functionality of Angiotensin Converting Enzyme 2-Angiotensin-(1–7)-Mas Axis in Diabetic Rat Carotid

Table 1

Fasting blood glucose levels from control or diabetic rats.

Rats	Glycaemia (mg·dL^−1)
	Day 0	Day 2
Nontreated Control	68.7±3.11	73.0±6.35
Nontreated Diabetic	75.4±5.17	392.6±11.47^∗,#
DX600-treated control	70.5±4.20	71.8±5.23
DX600-treated diabetic	69.9±6.31	402.7±15.25^∗,#
Angiotensin-(1–7)-treated control	73.1±5.19	67.9±5.24
Angiotensin-(1–7)-treated diabetic	71.2±4.98	385.9±13.26^∗,#
A779-treated control	72.1±4.57	76.3±7.93
A779-treated diabetic	74.2±7.21	406.0±14.69^∗,#
Angiotensin-(1–7) + A779-treated control	67.5±6.52	69.3±6.45
Angiotensin-(1–7) + A779-treated diabetic	71.2±7.09	409.1±17.33^∗,#

The values are significantly different (𝑃<0.01; 𝑛=11) from the respective control rats at the same day (*) or the same rats at day 0 (#).