Azadirachta indica Attenuates Cisplatin-Induced Nephrotoxicity and Oxidative Stress

Table 2

Protective effects of methanolic leaves extract of neem on cisplatin-induced alternation in kidney function parameters of rats.

Groups	Uric acid (mg/dL)	Urea (mg/dL)	Creatinine (mg/dL)
Con	55.76±2.63	2.97±0.15	0.55±0.04
CP	89.86±4.69^a	5.83±0.29^a	0.83±0.04^a
N-CP	71.64±3.17^ab	4.30±0.26^ab	0.71±0.03^ab
CP-N	65.62±2.39^ab	3.47±0.18^ab	0.64±0.02^ab

Values are mean ± SEM (𝑛=7).
^a𝑃<0.05, significant change with respect to control; ^b𝑃<0.05, significant change with respect to CP for Duncan’s post hoc test.