In Vitro and In Vivo Effects of Suppressor of Cytokine Signalling 7 Knockdown in Breast Cancer: The Influence on Cellular Response to Hepatocyte Growth Factor

Table 7

The in vitro migration rate of MCF7 (𝜇m/hr). Values represent Mean (SD).

Cell lines		MCF7^ΔSOCS7		𝑃
	Incubation medium	HGF
MCF7^pEF6	HGF	97  (18)  vs. 62.9 (19.3)		0.008
Cell lines		MCF7^pEF6	MCF7^ΔSOCS7	𝑃
		HGF
MCF7^pEF6	Serum free only	62.9  (19.3)  vs. 37 (17.6)		0.026
MCF7^ΔSOCS7			97  (18)  vs. 83.9 (37.5)	0.252
		Pretreatment with U73122 then HGF
MCF7^pEF6	HGF	46.9  (14.2)  vs. 62.9 (19.3)		0.184
MCF7^ΔSOCS7			60.3  (21.6)  vs. 97 (18)	0.005